THE SCIENCE - Collagenade

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THE SCIENCE BEHIND COLLAGENADE^®
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Collagenade^® is formulated using Verisol^® Collagen, a patented bioactive ingredient, easy to drink, soluble collagen.

Collagen is a major component of the human body. About 30% of our total body protein is collagen. Collagen is crucial for mobile joints, stable bones, healthy muscles, strong ligaments and tendons, smooth skin, glossy hair and healthy finger nails. It is one of the primary structural proteins of connective tissues and also abundant in blood vessels, intervertebral discs, the blood-brain barrier, the cornea, dentin and the intestinal wall – a vital component of our whole body.

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REDUCTION OF WRINKLES²

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The second study with more than 100 women aged between 45 and 65 years shows that the oral administration of VERISOL^® (2.5 g/day) significantly reduces wrinkles after 4 weeks and leads to a significantly higher skin pro-collagen concentration.

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²Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis Proksch E., Schunck M., Zague V., Segger D., Degwert J., Oesser S. Skin Pharmacol Physiology, December 2013

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SIGNIFICANT IMPROVEMENT IN SKIN HEALTH

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VERISOL^® consists of special collagen peptides – important components for supporting healthy skin. Administered orally, VERISOL^® influences the skin’s collagen metabolism directly from the inside. It increases the skin moisture and delays the formation of wrinkles. Several scientific experiments investigated the potential of VERISOL^®.

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HIGHER SKIN ELASTICITY¹

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The first study with 69 women aged between 35 and 55 years revealed that VERISOL^® leads to significantly higher skin elasticity – up to 15% – compared to placebo treatment. This effect could be measured after just 4 weeks of treatment and persisted after 8 weeks of oral VERISOL^®administration. Another 4 weeks after the last intake of the product, VERISOL^®application still showed higher skin elasticity levels than in the placebo treated group.

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¹Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study Proksch E., Segger D., Degwert J., Schunck M., Zague V., Oesser S. Skin Pharmacol Physiology, August 2013

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SIGNIFICANT DECREASE OF CELLULITE³

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A double blind, randomized, placebo controlled study with 105 women aged between 25 and 50 years shows that the daily oral intake of 2.5g VERISOL^® significantly decreases the cellulite score. The effect was measured after 3 and 6 months supplementation. VERISOL^® has a beneficial effect on skin extracellular matrix and restores the normal structure of the dermis and subcutaneous tissue. VERISOL^® supplementation also reduced the waviness of the skin, with first results visible after 3 months, but more pronounced after 6 months. With a daily dose of 2.5g VERISOL^® the appearance of cellulite women with a BMI <25 was significantly reduced.As part of the study, changes in the dermal density were investigated. The two ultrasound scans show side by side the skin of a participant in the placebo group compared to the skin of a participant from the VERISOL^® group. The increase in elastin and collagen is clearly visible.

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³JOURNAL OF MEDICINAL FOOD, J Med Food 00 (0) 2015, 1–9, DOI: 10.1089/jmf.2015.0022, Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology Michael Schunck, 1 Vivian Zague, 2 Steffen Oesser, 1 Ehrhardt Proksch, 3

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IMPROVED SKIN SURFACE STRUCTURE AND DECREASE OF CELLULITE

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About 85% of the global female adult population is affected by cellulite (the orange peel appearance of skin). Cellulite is a beauty aspect, not a disease, but many women suffer from this beauty flaw. Cellulite is mainly caused by dermal matrix disturbances, in combination with excess of subcutaneous fat, bulging into the dermis as well as excess of intersistal fluid. VERISOL^® supplementation has beneficial effects on the dermal extracellular matrix of the skin and can help to decrease cellulite. Contrary to current cellulite supplements that mainly address the aspects of excessive fat or microcirculation/ drainage, VERISOL^® directly stimulates the extracellular matrix formation in skin.

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PROMOTING GROWTH AND HEALTH OF FINGER NAILS⁴

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For many women, well-groomed fingernails are an inseparable part of an attractive appearance. But many women suffer from cracked or chipped nails as well as nail peeling and nail roughness. The Bioactive Collagen Peptides^® VERISOL^® can help to improve growth and health of fingernails. The different positive effects of VERISOL^® are shown in a recent study. The study shows a decrease of cracked and/or chipped nails after 2 months of treatment, reaching a decrease of 42% after 6 months. Compared to the control group, the nail growth speed is increasing. VERISOL^® led to a statistically significant improvement in nail growth after 3 months of treatment.

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At the same time, there’s a notable improvement in nail peeling and a clearly decreased nail edge irregularity. 80% of the patients were completely satisfied and satisfied with VERISOL^® treatment. 75% of the women perceive their nails as longer, 71% said their nails grew faster and became longer.

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⁴One-Way ANOVA, Fischer post-test, publication pending

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